An anthology horror drama series centering on different characters and locations, including a house with a murderous past, an asylum, a witch coven, a freak show, a hotel, a farmhouse in Roanoke, a cult, the apocalypse and a summer camp.
A therapist and his family move across the country to escape their troubled past but quickly discover that their new home comes with its own horrific baggage.
Vivien and Violet get themselves caught in a dangerous situation. Meanwhile, Ben goes back to Boston to fix a mistake that he made.
Vivien learns the horrific truth about the house's first residents and Ben's visitor causes him to further unravel about what really happened in the haunted house. Constance and Moira have their history revealed.
The line between the living and the dead blurs on Halloween. Two of the house's previous residents give the Harmons decorating advice.
Tate comes face to face with his past, and Ben and Vivien are haunted by a new houseguest before Halloween night comes to an end.
Constance enlists Violet's assistance with Tate. Ben helps a new patient confront his fears.
Moira persuades a buyer to make an offer while Constance and Larry work against her efforts.
The man in the rubber suit is revealed.
One of history's most famous murder victims pays the house a visit. Constance discovers more of Tate's bad behavior.
Violet learns about the rules of the house. The truth about Larry's condition is explained. Constance is interrogated by the police.
Vivien gives birth. Tate and Violet attempt to rid the house of some of its ghosts for good.
In the aftermath of family tragedy, Ben tries to take his child out of the Murder House. Meanwhile, Violet and Vivien accustom themselves to their new living arrangements, Constance raises Tate's child as her own and a new family buys the house.